Human genomes: what do we share and where do we differ?

Most human DNA is shared. A research institute’s introduction helps explain differences without turning genetic comparison into a label for a person.

Concept illustration · Original evidence is linked below.

Most DNA is shared

NHGRI describes human genomes as highly similar, with variation at several scales. A single summary percentage depends on which kinds of differences are included. National Human Genome Research Institute ↗

A reference is a comparison tool

A reference genome is not a complete representation of every population. The pangenome approach seeks to represent a wider range of variation. National Human Genome Research Institute ↗

Do not turn a comparison into an identity

When reading an ancestry visualization, ask what was sampled and what the comparison measures. Genetic similarity does not independently identify a language, religion, or polity. National Human Genome Research Institute ↗

Sources to Explore

Microbes and human migrationHuman origins: why does the model include several groups?How do you know a language that left no texts?Is there a mother of all languages?More from Across regions on the timelineSee every guide on the timeline
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